Publications

King, R. W.;  Bauer, J. D.; Brady, S. F., An environmental DNA-derived type II polyketide biosynthetic pathway encodes the biosynthesis of the pentacyclic polyketide erdacin. Angewandte Chemie 2009, 48 (34), 6257-61. 10.1002/anie.200901209

Craig, J. W.;  Chang, F. Y.; Brady, S. F., Natural products from environmental DNA hosted in Ralstonia metallidurans. ACS chemical biology 2009, 4 (1), 23-8. 10.1021/cb8002754

Brady, S. F.;  Simmons, L.;  Kim, J. H.; Schmidt, E. W., Metagenomic approaches to natural products from free-living and symbiotic organisms. Natural product reports 2009, 26 (11), 1488-503. 10.1039/b817078a

Clarke-Pearson, M. F.; Brady, S. F., Paerucumarin, a new metabolite produced by the pvc gene cluster from Pseudomonas aeruginosa. Journal of bacteriology 2008, 190 (20), 6927-30. 10.1128/JB.00801-08

Banik, J. J.; Brady, S. F., Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary. Proceedings of the National Academy of Sciences of the United States of America 2008, 105 (45), 17273-7. 10.1073/pnas.0807564105

Singh, M. P.;  Janso, J. E.; Brady, S. F., Cytoskyrins and cytosporones produced by Cytospora sp. CR200: taxonomy, fermentation and biological activities. Marine drugs 2007, 5 (3), 71-84.

Clardy, J.; Brady, S. F., Cyclic AMP directly activates NasP, an N-acyl amino acid antibiotic biosynthetic enzyme cloned from an uncultured beta-proteobacterium. Journal of bacteriology 2007, 189 (17), 6487-9. 10.1128/JB.00457-07

Brady, S. F.;  Bauer, J. D.;  Clarke-Pearson, M. F.; Daniels, R., Natural products from isnA-containing biosynthetic gene clusters recovered from the genomes of cultured and uncultured bacteria. Journal of the American Chemical Society 2007, 129 (40), 12102-3. 10.1021/ja075492v

Brady, S. F., Construction of soil environmental DNA cosmid libraries and screening for clones that produce biologically active small molecules. Nature protocols 2007, 2 (5), 1297-305. 10.1038/nprot.2007.195

Maloney, K. N.;  Hao, W.;  Xu, J.;  Gibbons, J.;  Hucul, J.;  Roll, D.;  Brady, S. F.;  Schroeder, F. C.; Clardy, J., Phaeosphaeride A, an inhibitor of STAT3-dependent signaling isolated from an endophytic fungus. Organic letters 2006, 8 (18), 4067-70. 10.1021/ol061556f